The NFL returns to Mexico as the San Francisco 49ers host the Minnesota Vikings

Mexico City is back on the NFL map with a blockbuster primetime matchup. According to multiple reports ahead of Wednesday's official schedule release, the Minnesota Vikings will travel to the Mexican capital to face the San Francisco 49ers on Sunday, November 22. 

This Week 11 clash is set to take center stage as a Sunday Night Football special, marking a triumphant return to the newly renovated Banorte Stadium (formerly Estadio Azteca).

The 49ers, long considered Mexico’s most popular team, are embracing an unprecedented international itinerary in 2026. Kyle Shanahan’s squad will make history by playing in both the season opener in Melbourne, Australia, and the final international game of the year in Mexico City. 

While early rumors suggested matchups against the Raiders or Dolphins, the league’s decision to pit the 49ers against a formidable NFC contender like the Vikings underscores the prestige of the Mexican market.

For the Vikings, this marks their first-ever regular-season appearance in Mexico, a key pillar in the franchise's global expansion strategy. Historically, these two teams have a storied rivalry; while the 49ers hold a perfect 5-0 postseason record against Minnesota, the Vikings have claimed victory in their last two regular-season meetings. 

With playoff implications likely on the line by late November, this "South of the Border" showdown is set to be the crown jewel of the 2026 International Series.